{"id":3613,"date":"2025-07-31T15:34:39","date_gmt":"2025-07-31T13:34:39","guid":{"rendered":"https:\/\/beta.pharmadiet.com\/?post_type=product&#038;p=3613"},"modified":"2025-11-17T13:33:16","modified_gmt":"2025-11-17T12:33:16","slug":"hyaloral-large-giant","status":"publish","type":"product","link":"https:\/\/beta.pharmadiet.com\/uk\/productos\/hyaloral-large-giant\/","title":{"rendered":"Hyaloral\u00ae Large and Giant breeds"},"content":{"rendered":"<p>Hyaloral\u00ae supports the proper development and maintenance of joints, tendons, and ligaments. Supplement for larger dogs.<\/p>\n<ul>\n<li>Clinical evidence demonstrated in our own study with Hyaloral\u00ae<sup>1<\/sup><\/li>\n<li>Ingredients with clinical studies<\/li>\n<li>Palatability tolerated satisfactorily in dogs with Hyaloral\u00ae<sup>2,3<\/sup><\/li>\n<li>Suitable modes of use according to the weight of the pet<\/li>\n<li>Easily divisible tablets.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Complementary food whose added nutrients to the regular diet contribute to the proper development and maintenance of joints, tendons, and ligaments. Supplement for larger dogs<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"featured_media":3615,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"animal":[119],"product_brand":[],"product_cat":[20],"product_tag":[277],"class_list":{"0":"post-3613","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"animal-dog","7":"product_cat-joint-supplements-animals","8":"product_tag-plantillaa","9":"desktop-align-left","10":"tablet-align-left","11":"mobile-align-left","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"acf":{"title_indications":"","description_indication":"","items_indication":[{"imagen":3616,"title":"What is canine hip dysplasia?","description":"Canine hip dysplasia is an orthopedic condition in which the affected joint, usually the hips and elbows, do not develop correctly. This can lead to joint cartilage degeneration, pain, inflammation, and difficulty in movement. It is more common in large breeds (larger in size) and may be hereditary.\r\n\r\nDiagnosis is made through radiographs and treatment may include dietary changes, medications, and surgery. Early detection of hip or elbow dysplasia and veterinary care are essential to improve the dog's quality of life, maintaining its physical, mental, and emotional well-being."}],"title_beneficios":"How does this complementary feed help your pet's joint health?","description_benefits":"Complementary feed with nutrients to aid in the proper development of joints, tendons, cartilage, and ligaments, designed for the joints of dogs.\r\n\r\n&nbsp;","items_benefits":[{"imagen":1268,"title":"Contributes to Healthy Development","description":"Helps maintain the health of joints, tendons, cartilage, and ligaments, especially important in growing young animals.\r\n\r\n&nbsp;"},{"imagen":3617,"title":"Aids in Maintaining Mobility","description":"By maintaining joint health, it helps with flexibility, reducing stiffness in older animals.\r\n\r\n&nbsp;"},{"imagen":1269,"title":"Maintenance of Joint Health","description":"Helps maintain joint health over time by helping prevent or delay joint problems.\r\n\r\n&nbsp;"},{"imagen":1246,"title":"Contributes to Prevention of Dysplasia","description":"Helps maintain joint health from an early age, contributing to the prevention of canine and feline dysplasia, a common orthopedic disorder in some breeds. This enables your pets to maintain strong and functional joints throughout their lives.\r\n\r\n&nbsp;"},{"imagen":1272,"title":"Supports an Active Life","description":"Facilitates an active lifestyle, allowing your pets to enjoy physical activities such as playing, running, and jumping with greater comfort, contributing to their physical and emotional well-being."}],"items_presentaciones":[{"title":"Hyaloral\u00ae Large and Giant breeds","description":"Boxes with 120 or 360 tablets of 4.5 g each, easily divisible to facilitate intake.\r\n\r\n&nbsp;","imagen":3615}],"description_ingredients":"","items_ingredients":[{"title":"Hyaluronic Acid<sup>4,5,6,7,8<\/sup>","description":"Main component of synovial fluid in the joints, with viscoelastic and lubricating properties. Its oral intake helps facilitate joint movement due to its viscosity; protect cartilage from wear; reduce inflammation; and promote cartilage nutrition.\r\n\r\nHyaluronic Acid provides viscoelasticity to synovial fluid and is responsible for lubricating the synovial membrane and articular cartilage. Oral intake has been shown to be effective in osteoarthritis in dogs."},{"title":"Hydrolyzed Enzymatically Collagen\r\n\r\n&nbsp;","description":"Major component and structural basis of hyaline cartilage in the joints, the main tissue affected in joint degeneration processes. Hydrolyzed collagen is known to maintain cartilage integrity and provides flexibility, elasticity, and support. Its administration allows for greater absorption, distribution, and accumulation in articular cartilage."},{"title":"Glucosamine\r\n\r\n&nbsp;","description":"Amino sugar component of articular cartilage, substrate, and stimulator of the synthesis of chondroitin and hyaluronic acid. It protects hyaline cartilage from wear and promotes cartilage nutrition.\r\n\r\n&nbsp;"},{"title":"Chondroitin Sulfate","description":"Main glycosaminoglycan of the extracellular matrix of cartilage. Nutrient that contributes to the formation of different components of cartilage, helps decrease cartilage destruction, and reduces inflammation by decreasing the action of proinflammatory molecules."},{"title":"Gamma Oryzanol<sup>9,10,11<\/sup>","description":"A naturally derived substance that exhibits powerful antioxidant action, helps eliminate free radicals, and reduces inflammation.\r\n\r\nThe combination of chondroitin sulfate, glucosamine, and antioxidants in the diet improves the condition of the joints and is effective for treating dogs with osteoarthritis.\r\n\r\nGlucosamine and chondroitin have been shown to improve joint function and may be responsible for improving pain on manipulation, lameness, and range of motion."}],"video":"","items_Instructions_for_use":[{"title":"Dog","description":"Oral administration.\r\n<ul>\r\n \t<li>1 tablet per 20 kg of body weight per day in a single dose.<\/li>\r\n \t<li>Dogs weighing 40 kg or more: 2 tablets per day in a single dose.<\/li>\r\n<\/ul>\r\nIt is recommended to mix with regular food for a minimum of 3 months.\r\n\r\nAs it is a complementary feed, it can be taken continuously."}],"image_banner_scientific_study_copiar":3391,"title_banner_scientific_study":"Hyaloral FOPG Study","description_banner_scientific_study":"<h3><span style=\"color: #ffffff;\">What did we research?<\/span><\/h3>\r\nWe studied how our product Hyaloral, a complementary feed combining hyaluronic acid and hydrolyzed collagen, can prevent elbow dysplasia in dogs.\r\n<h3><span style=\"color: #ffffff;\">What were the study's conclusions?<\/span><\/h3>\r\n<ul>\r\n \t<li>The group supplemented with Hyaloral experienced a significant reduction in the occurrence of joint dysplasia, with a 95% probability of success.<\/li>\r\n \t<li>Additionally, our product proved effective in relieving symptoms of joint dysplasia.<\/li>\r\n<\/ul>\r\nDo you want to see all the details of our study? Click the button to view the complete study!","Scientific_study_banner":3393,"studies":[{"header_image":"","bibliography_image":1261,"title":"Hyaloral FOPG Study","study":3393}],"bibliografy_text":"<ol>\r\n \t<li>Efficacy of an oral hyaluronate and collagen supplement as a preventive treatment of elbow dysplasia. Sim\u00f3n Mart\u00ed-Angulo, N\u00faria Garc\u00eda-L\u00f3pez, Ana D\u00edaz-Ramos. J. Vet. Sci. (2014), 15(4), 569-574.<\/li>\r\n \t<li>Estudio palatabilidad gatos<\/li>\r\n \t<li>\u00a0Estudio palatabilidad perros<\/li>\r\n \t<li>Alves JC, Dos Santos AMMP, Jorge P, Lavrador CFTVB, Carreira LM. Effect of a single intra-articular high molecular weight hyaluronan in a naturally occurring canine osteoarthritis model: a randomized controlled trial. J Orthop Surg Res. 2021 May 3;16(1):290. doi: 10.1186\/s13018-021-02423-4. PMID: 33941219; PMCID: PMC8091761.<\/li>\r\n \t<li>Alves et al. Effect of an oral joint suplement when compared to another product in the management of hip osteoarthritis in working dogs. Topics in Compan An Med 32 (2017) 126-129.<\/li>\r\n \t<li>Bergin et al. Oral hyaluronan gel reduces post-operative tarsocrural effusion in the yearling Thoroghbred. Equine Vet J, 2006 38 (4): 375-378.<\/li>\r\n \t<li>Carmona et al. Efectos bioqu\u00edmicos y Cl\u00ednicos del hialuronato oral en Caballos andaluces j\u00f3venes con osteocondrosis tarsocrural. Arch Med Vet, 2009, 41, 139-14<\/li>\r\n \t<li>Martello, E., Bigliati, M., Adami, R., Biasibetti, E., Bisanzio, D., Meineri, G., &amp; Bruni, N. (2022). Efficacy of a dietary supplement in dogs with osteoarthritis: A randomized placebo-controlled, double-blind clinical trial. PloS one, 17(2), e0263971.\u00a0<a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0263971\">https:\/\/doi.org\/10.1371\/journal.pone.0263971<\/a><\/li>\r\n \t<li>Minatel et al. Antioxidant activity of \u01b3-Oryzanol: a complex network of interactions.\u00a0 Int J Mol Sci, 2016, 17, 1107.<\/li>\r\n \t<li>Parrado et al. Prevention of brain protein and l\u00edpid oxidation elicited by a water-soluble oryzanol enzymatic extract derived from rice bran. Eur J Nutr, 2003, 42: 307-314.<\/li>\r\n \t<li>Shin et al. \u01b3-Oryzanol supresses COX-2 expression by inhibiting reactive oxygen species-mediated Erk \u00bd and Egr-1 signaling in LPS-stimulated RAW264.7 macrophages. Biochem biophysic Research Communications, 2017, 491, 486-492<\/li>\r\n<\/ol>","features":[{"image":1270,"title":"Proven effectiveness in clinical study"},{"image":1271,"title":"Acceptance rate of 89% in dogs and cats"},{"image":1262,"title":"Chicken protein-free"},{"image":1267,"title":"Without preservatives."},{"image":1213,"title":"Easily divisible tablets."}],"ficha_tecnica":3614},"_links":{"self":[{"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/product\/3613","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/comments?post=3613"}],"version-history":[{"count":12,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/product\/3613\/revisions"}],"predecessor-version":[{"id":17398,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/product\/3613\/revisions\/17398"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/media\/3615"}],"wp:attachment":[{"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/media?parent=3613"}],"wp:term":[{"taxonomy":"animal","embeddable":true,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/animal?post=3613"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/product_brand?post=3613"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/product_cat?post=3613"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/beta.pharmadiet.com\/uk\/wp-json\/wp\/v2\/product_tag?post=3613"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}